Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156302 | 0.93 | USP30 (0.35) | KDM4EMAPTTHRBEPHX1PDE4B | |
| SCHEMBL5230446 | 0.76 | NR1H2 (0.38) | KDM4EGPR35NR1H2NR1H3 | |
| SCHEMBL2156912 | 0.76 | NR1H4 (0.31) | KDM4EUCHL1USP30HPGD | |
| SCHEMBL2986521 | 0.75 | NR1H2 (0.36) | MAPTTHRBUSP30NR1H2 | |
| SCHEMBL2157086 | 0.74 | KDM4E (0.35) | KDM4EMAPTHPGDFEN1 | |
| SCHEMBL2157499 | 0.73 | KDM4E (0.34) | KDM4EMAPTHPGD | |
| SCHEMBL5443997 | 0.73 | ALDH1A1 (0.39) | KDM4EMAPTUCHL1USP30HPGD | |
| SCHEMBL2156661 | 0.71 | ALDH1A1 (0.34) | KDM4EMAPTHPGD | |
| SCHEMBL2157156 | 0.70 | KDM4E (0.35) | KDM4EMAPTHPGD | |
| SCHEMBL2156309 | 0.70 | ALDH1A1 (0.43) | KDM4EMAPTNR1H2NR1H3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | disclosed |