Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 14/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156309 | 0.93 | ALDH1A1 (0.43) | NR1H2NR1H3ALDH1A1LMNAKDM4E | |
| SCHEMBL2986524 | 0.76 | ALDH1A1 (0.40) | NR1H2NR1H3ALDH1A1LMNAKDM4E | |
| SCHEMBL2156914 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4E | |
| SCHEMBL2157504 | 0.73 | KDM4E (0.39) | ALDH1A1LMNAKDM4EGRM6 | |
| SCHEMBL2157091 | 0.72 | KDM4E (0.43) | ALDH1A1LMNAKDM4E | |
| SCHEMBL2998154 | 0.70 | MEN1 (0.40) | ALDH1A1LMNABCHEKDM4E | |
| SCHEMBL2156666 | 0.70 | KMT2A (0.39) | ALDH1A1LMNAKDM4E | |
| SCHEMBL26963375 | 0.69 | TSHR (0.39) | ALDH1A1LMNAKDM4E | |
| SCHEMBL2157158 | 0.69 | KDM4E (0.42) | ALDH1A1LMNAKDM4E | |
| SCHEMBL28786590 | 0.69 | DAO (0.36) | NR1H2NR1H3ALDH1A1BCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | disclosed |