Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.51 |
| ▸ | PPARD | Q03181 | 14/20 | 0.47 |
| ▸ | PPARA | Q07869 | 12/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010083 | 0.82 | PPARG (0.53) | PPARGPPARDPPARA | |
| SCHEMBL2004288 | 0.80 | MTNR1A (0.40) | PPARDPPARAGRIN2B | |
| SCHEMBL2002556 | 0.79 | PPARG (0.47) | PPARGPPARDPPARAGRIN2BITGB3 | |
| SCHEMBL1400840 | 0.77 | PPARA (0.64) | PPARGPPARDPPARA | |
| SCHEMBL2004368 | 0.77 | APP (0.35) | PPARDPPARAGRIN2B | |
| SCHEMBL12568430 | 0.76 | PPARD (0.48) | PPARGPPARDPPARAGRM2MCL1 | |
| SCHEMBL12568696 | 0.75 | PPARD (0.62) | PPARGPPARDPPARA | |
| SCHEMBL12568704 | 0.74 | PPARD (0.53) | PPARGPPARDPPARAGRIN2B | |
| SCHEMBL2004366 | 0.74 | MTNR1A (0.39) | — | |
| SCHEMBL12568713 | 0.74 | ITGB3 (0.46) | PPARGPPARDPPARAITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620088-A4 | INDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS | BAYER PHARMACEUTICALS CORP (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-1620088-A2 | INDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS | Bayer Pharmaceuticals Corporation (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098498-A2 | INDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |