Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998597 | 0.85 | AAK1 (0.33) | AAK1SCN9A | |
| SCHEMBL5234576 | 0.80 | SCN9A (0.36) | SCN9A | |
| SCHEMBL5227012 | 0.77 | CYP3A4 (0.40) | SCN9A | |
| SCHEMBL791480 | 0.73 | SCN9A (0.46) | SCN9A | |
| SCHEMBL12894489 | 0.73 | SCN9A (0.50) | AAK1SCN9A | |
| SCHEMBL5234397 | 0.67 | CNR1 (0.36) | — | |
| SCHEMBL5233817 | 0.66 | CYP2D6 (0.38) | — | |
| SCHEMBL5234725 | 0.66 | EGFR (0.42) | — | |
| SCHEMBL5230063 | 0.66 | EGFR (0.41) | — | |
| SCHEMBL5236137 | 0.65 | GRIN1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |