Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233817 | 0.85 | CYP2D6 (0.38) | ALDH1A1LMNAKCNH2MAPT | |
| SCHEMBL2998608 | 0.85 | CNR1 (0.37) | CNR1CNR2ERCC5FEN1KDM4E | |
| SCHEMBL5234576 | 0.83 | SCN9A (0.36) | CNR1ALDH1A1FABP4MAPTPOLB | |
| SCHEMBL5230063 | 0.82 | EGFR (0.41) | CYP3A4MAPTHSD17B10 | |
| SCHEMBL5227499 | 0.79 | TSPO (0.34) | KCNH2MAPT | |
| SCHEMBL5232300 | 0.79 | CYP2D6 (0.33) | CNR1KCNH2MAPT | |
| SCHEMBL5231037 | 0.79 | GRIN2B (0.38) | KCNH2MAPT | |
| SCHEMBL13211511 | 0.78 | ALDH1A1 (0.37) | CNR2FEN1KDM4EMEN1ALDH1A1 | |
| SCHEMBL428662 | 0.78 | NR4A2 (0.44) | KDM4EKMT2A | |
| SCHEMBL5231149 | 0.77 | GRIN2B (0.39) | KDM4EALDH1A1LMNACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |