Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 12/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | HRH2 | P25021 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232705 | 0.88 | MEN1 (0.53) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL5237792 | 0.86 | GRM5 (0.50) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL5235707 | 0.84 | L3MBTL1 (0.51) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL5229150 | 0.83 | TMEM97 (0.56) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL28706501 | 0.82 | TMEM97 (0.55) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL5237843 | 0.82 | KMT2A (0.54) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL5235413 | 0.82 | TMEM97 (0.51) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL28695496 | 0.82 | ME2 (0.60) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL19211095 | 0.82 | MEN1 (0.56) | TMEM97SIGMAR1HTR1AADRA2CHRH2 | |
| SCHEMBL22291054 | 0.81 | CA1 (0.55) | TMEM97SIGMAR1HTR1AADRA2CHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |