Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809673 | 0.94 | ESR1 (0.63) | MAPTESR1STS | |
| SCHEMBL16632439 | 0.91 | ALDH1A1 (0.67) | MAPTNPC1RAB9AALDH1A1ESR1 | |
| SCHEMBL16632600 | 0.91 | ALDH1A1 (0.67) | MAPTNPC1RAB9AALDH1A1ESR1 | |
| SCHEMBL30316540 | 0.91 | ALDH1A1 (0.67) | MAPTNPC1RAB9AALDH1A1ESR1 | |
| SCHEMBL9458337 | 0.91 | ALDH1A1 (0.67) | MAPTNPC1RAB9AALDH1A1ESR1 | |
| SCHEMBL9458677 | 0.91 | ALDH1A1 (0.67) | MAPTNPC1RAB9AALDH1A1ESR1 | |
| SCHEMBL9458309 | 0.91 | ALDH1A1 (0.67) | MAPTNPC1RAB9AALDH1A1ESR1 | |
| SCHEMBL9458671 | 0.91 | ALDH1A1 (0.67) | MAPTNPC1RAB9AALDH1A1ESR1 | |
| SCHEMBL4853372 | 0.91 | ALDH1A1 (0.67) | MAPTNPC1RAB9AALDH1A1ESR1 | |
| SCHEMBL9458998 | 0.90 | NPC1 (0.64) | MAPTNPC1RAB9AALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394158-B1 | Thiophene derivatives and optical elements using the same | FUJIFILM CORP (JP) | 2007-03-21 | — | — | EP | disclosed |
| EP-1394158-A1 | Novel compounds and optical elements using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |