Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523092 | 1.00 | ALOX15 (0.49) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL1150421 | 1.00 | ALOX15 (0.49) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL1150423 | 1.00 | ALOX15 (0.49) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL11844978 | 0.88 | ALOX15 (0.45) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL11844971 | 0.88 | ALOX15 (0.45) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL7933532 | 0.87 | ALOX15 (0.50) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL7933530 | 0.87 | ALOX15 (0.50) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL9578903 | 0.87 | ALOX15 (0.50) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL9578905 | 0.87 | ALOX15 (0.50) | ALOX15ALDH1A1FNTAFNTBUSP2 | |
| SCHEMBL11755839 | 0.87 | KDM4E (0.46) | ALOX15ALDH1A1FNTAFNTBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417082-B1 | CATALYTIC WITTIG AND MITSUNOBU REACTIONS | UNIV TEXAS (US) | 2016-03-16 | — | — | EP | disclosed |
| US-8901365-B2 | Catalytic Wittig and Mitsunobu reactions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-12-02 | — | — | US | disclosed |
| EP-2417082-A2 | CATALYTIC WITTIG AND MITSUNOBU REACTIONS | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20120029211-A1 | Catalytic Wittig and Mitsunobu Reactions | THE UNIVERSITY OF TEXAS AT ARLINGTON | 2012-02-02 | — | — | US | disclosed |
| US-20110028746-A1 | METHOD FOR THE DECARBOXYLATIVE HYDROFORMYLATION OF ALPHA, BETA- UNSATURATED CARBOXYLIC ACIDS | BASF SE (DE) | 2011-02-03 | — | — | US | disclosed |
| WO-2010118042-A2 | CATALYTIC WITTIG AND MITSUNOBU REACTIONS | BOARD OF REGENTS THE UNIVERSITY OF TEXAS AT ARLINGTON (US) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028746-A1 | METHOD FOR THE DECARBOXYLATIVE HYDROFORMYLATION OF ALPHA, BETA- UNSATURATED CARBOXYLIC ACIDS | PCCA, CBR3, CBR1 | ALOX15 717/4885ALDH1A1 367/4885FNTA 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.