Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230967 | 1.00 | AKR1C3 (0.42) | AKR1C3MEN1KMT2AMAPTHTT | |
| SCHEMBL5230594 | 0.95 | MEN1 (0.45) | MEN1KMT2AMAPTHTTKDM4E | |
| SCHEMBL5230601 | 0.95 | MEN1 (0.45) | MEN1KMT2AMAPTHTTKDM4E | |
| SCHEMBL5230605 | 0.95 | MEN1 (0.45) | MEN1KMT2AMAPTHTTKDM4E | |
| SCHEMBL5236079 | 0.85 | CDK8 (0.46) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL5236086 | 0.85 | CDK8 (0.46) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL5234409 | 0.79 | AKR1C3 (0.50) | AKR1C3MEN1KMT2AMAPTHTT | |
| SCHEMBL5235406 | 0.78 | ALDH1A1 (0.36) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL5232551 | 0.73 | MAPT (0.53) | AKR1C3MEN1KMT2AMAPTHTT | |
| SCHEMBL5235602 | 0.71 | AKR1C3 (0.44) | AKR1C3MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |