SCHEMBL5231

SCHEMBL5231

[CH2]C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28252509 0.94
SCHEMBL7438940 0.78
Urea SCHEMBL11859745 0.75 LMNA (0.75)
Urea SCHEMBL687586 0.75
Urea SCHEMBL28335895 0.75 LMNA (0.75)
Urea SCHEMBL3426239 0.75 LMNA (0.75)
Urea SCHEMBL36685 0.75
Urea SCHEMBL6845937 0.75 LMNA (0.75)
Urea SCHEMBL20456 0.75
Urea SCHEMBL4454525 0.75 LMNA (0.75)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13155 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
WO-2024148272-A1 AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC (US) 2024-07-11 WO claimed
US-20240218022-A1 ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-04 US claimed
US-20240209005-A1 BICYCLIC HETEROARYL BORONATE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC 2024-06-27 US claimed
US-20240209009-A1 PEPTIDES COMPRISING A PHOSPHORYLCHOLINE CONJUGATE AND METHODS OF SYNTHESIZING SAME TARSIER PHARMA LTD. (IL) 2024-06-27 US claimed
CN-115466251-B Condensed heterocyclic compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-06-21 CN claimed
CN-114591318-B Pyrazolo heterocyclic compound, preparation method thereof, pharmaceutical composition and application 中国医学科学院药物研究所 2024-06-21 CN claimed
CN-114507227-B Benzisothiazole compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-06-21 CN claimed
US-20240197666-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-GEN THERAPEUTICS, INC. (US) 2024-06-20 US claimed
US-20240199661-A1 BICYCLIC HETEROARYL PHOSPHONATE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC 2024-06-20 US claimed
US-4140797-A MERCAPTOACYL AMINO ACIDS, ENZYME INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1979-02-20 US claimed
EP-0000005-A1 New cephalosporin derivatives, their preparations and their pharmaceutical compositions F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1978-12-20 EP claimed
US-4065255-A HUMAN HAIR L'OREAL (FR) 1977-12-27 US claimed
US-4065254-A DIAZO DYES, LEATHER, COTTON, WOOL CIBA-GEIGY CORPORATION (US) 1977-12-27 US claimed
US-4053469-A BACTERICIDES SHIONOGI & CO., LTD. (JA) 1977-10-11 US claimed
US-3987039-A ANTIBACTERIAL SHIONOGI & CO., LTD. (JA) 1976-10-19 US claimed
US-3973968-A YELLOW KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-08-10 US claimed
US-3961879-A P-PHENYLENEDIAMINE, HAIR L'OREAL (FR) 1976-06-08 US claimed
US-3948596-A Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler SOCIETE ANONYME DITE: L'OREAL (FR) 1976-04-06 US claimed
US-3931215-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed