Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LPO | P22079 | 2/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670943 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL3400913 | 0.81 | CYP1A2 (0.34) | SMN1; SMN2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL11536106 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL3397905 | 0.79 | RAB9A (0.33) | SMN1; SMN2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL27788621 | 0.79 | CYP1A2 (0.36) | SMN1; SMN2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL8503637 | 0.78 | RAB9A (0.55) | SMN1; SMN2RAB9ANPC1CYP1A2CYP2C19 | |
| SCHEMBL1078937 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL4675474 | 0.76 | ALDH1A1 (0.40) | CYP1A2TP53HPGD | |
| SCHEMBL13255594 | 0.74 | CYP1A2 (0.33) | SMN1; SMN2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL27472573 | 0.69 | SMN1; SMN2 (0.33) | SMN1; SMN2CYP1A2CYP3A4CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070068-B2 | GRANULATIMIDE DERIVATIVES FOR USE IN CANCER TREATMENT | UNIV BRITISH COLUMBIA (CA) | 2007-01-17 | — | — | EP | disclosed |
| EP-1070068-B1 | GRANULATIMIDE DERIVATIVES FOR USE IN CANCER TREATMENT | UNIV BRITISH COLUMBIA (CA) | 2003-10-08 | — | — | EP | disclosed |
| EP-1070068-A1 | GRANULATIMIDE DERIVATIVES FOR USE IN CANCER TREATMENT | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999047522-A1 | GRANULATIMIDE DERIVATIVES FOR USE IN CANCER TREATMENT | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1999-09-23 | — | — | WO | disclosed |