Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235842 | 1.00 | KDM4E (0.31) | KDM4ELMNAALDH1A1MEN1NPC1 | |
| SCHEMBL5235781 | 0.92 | ALDH1A1 (0.34) | KDM4ELMNAALDH1A1MEN1NPC1 | |
| SCHEMBL5233606 | 0.88 | — | — | |
| SCHEMBL5232766 | 0.88 | — | — | |
| SCHEMBL5234194 | 0.88 | OPRM1 (0.37) | KDM4EALDH1A1KMT2AMAOB | |
| SCHEMBL5232176 | 0.88 | MEN1 (0.36) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL5232191 | 0.88 | MEN1 (0.36) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL5232188 | 0.88 | MEN1 (0.36) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL5234148 | 0.88 | MEN1 (0.36) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL14459848 | 0.85 | NPSR1 (0.38) | LMNAALDH1A1MEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730116-B1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-09-05 | — | — | EP | claimed |