Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029374 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAANPC1RAB9A | |
| SCHEMBL5233189 | 0.76 | RECQL (0.40) | TAAR1POLBGAAL3MBTL1RECQL | |
| SCHEMBL5033798 | 0.76 | RECQL (0.40) | TAAR1POLBGAAL3MBTL1RECQL | |
| SCHEMBL3641064 | 0.73 | TAAR1 (0.65) | ALDH1A1MAPTKDM4ETAAR1POLB | |
| SCHEMBL991353 | 0.73 | TAAR1 (0.65) | ALDH1A1MAPTKDM4ETAAR1POLB | |
| SCHEMBL991352 | 0.73 | TAAR1 (0.65) | ALDH1A1MAPTKDM4ETAAR1POLB | |
| SCHEMBL6021781 | 0.72 | GPR119 (0.48) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL6021777 | 0.72 | GPR119 (0.48) | ALDH1A1MAPTKDM4EPOLBGAA | |
| Hydrochloric Acid SCHEMBL993335 | 0.72 | TAAR1 (0.63) | ALDH1A1MAPTKDM4ETAAR1POLB | |
| Hydrochloric Acid SCHEMBL993334 | 0.72 | TAAR1 (0.63) | ALDH1A1MAPTKDM4ETAAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656138-A4 | SUBSTITUTED CYCLOALKYAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-1656138-A2 | SUBSTITUTED CYCLOALKYAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005020899-A2 | SUBSTITUTED CYCLOALKYAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |