Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCRL2 | O00421 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031757 | 0.84 | CCRL2 (0.59) | CCRL2 | |
| SCHEMBL5031755 | 0.84 | CCRL2 (0.59) | CCRL2 | |
| SCHEMBL5033643 | 0.83 | CCRL2 (0.56) | CCRL2 | |
| SCHEMBL5033640 | 0.83 | CCRL2 (0.56) | CCRL2 | |
| SCHEMBL5031854 | 0.83 | CCR2 (0.55) | CCRL2 | |
| SCHEMBL5031849 | 0.83 | CCR2 (0.55) | CCRL2 | |
| SCHEMBL5029605 | 0.83 | CCR2 (0.63) | CCRL2 | |
| SCHEMBL5029600 | 0.83 | CCR2 (0.63) | CCRL2 | |
| SCHEMBL5031901 | 0.78 | CCRL2 (0.71) | CCRL2 | |
| SCHEMBL5228257 | 0.77 | CCR2 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656138-A4 | SUBSTITUTED CYCLOALKYAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-1656138-A2 | SUBSTITUTED CYCLOALKYAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005020899-A2 | SUBSTITUTED CYCLOALKYAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |