Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 6/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25994275 | 0.76 | CDK1 (0.45) | USP30CDK1BACE1RBP4GABRA1 | |
| SCHEMBL30847702 | 0.76 | CDK1 (0.45) | USP30CDK1BACE1RBP4GABRA1 | |
| SCHEMBL23959057 | 0.73 | CDK1 (0.46) | USP30CDK1BACE1GABRA1GABRG2 | |
| SCHEMBL6137318 | 0.71 | CDK1 (0.42) | USP30CDK1BACE1GABRA1GABRG2 | |
| SCHEMBL20571996 | 0.69 | KDM1A (0.42) | USP30BACE1RBP4GABRA1GABRG2 | |
| SCHEMBL30158232 | 0.69 | KDM1A (0.42) | USP30BACE1RBP4GABRA1GABRG2 | |
| SCHEMBL17792475 | 0.69 | USP30 (0.44) | USP30CDK1BACE1RBP4CCNB2 | |
| SCHEMBL2673664 | 0.67 | PDE5A (0.41) | USP30CDK1BACE1RBP4GABRA1 | |
| SCHEMBL31499359 | 0.67 | CDK1 (0.46) | CDK1BACE1ROCK2BCHECCNB2 | |
| SCHEMBL6137319 | 0.67 | HRH3 (0.37) | USP30CDK1BACE1RBP4GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412336-A4 | PEPTOID COMPOUNDS | UNIV WOLLONGONG (AU) | 2007-08-29 | — | — | EP | disclosed |
| EP-1412336-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003002545-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2003-01-09 | — | — | WO | disclosed |