Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.59 |
| ▸ | TACR1 | P25103 | 5/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237066 | 0.90 | DPP4 (0.56) | DPP4TACR1KCNA5KCNH2MAPK8 | |
| SCHEMBL5235258 | 0.87 | DPP4 (0.53) | DPP4TACR1KCNA5KCNH2MAPK8 | |
| SCHEMBL5237562 | 0.85 | DPP4 (0.52) | DPP4 | |
| SCHEMBL5237550 | 0.85 | DPP4 (0.52) | DPP4 | |
| Hydrochloric Acid SCHEMBL5235851 | 0.84 | DPP4 (0.76) | DPP4TACR1KCNA5KCNH2BRD4 | |
| SCHEMBL5237229 | 0.83 | DPP4 (0.56) | DPP4TACR1 | |
| SCHEMBL6107274 | 0.82 | DPP4 (0.55) | DPP4TACR1KCNA5KCNH2MAPK8 | |
| SCHEMBL7174997 | 0.81 | DPP4 (0.54) | DPP4TACR1KCNA5KCNH2MAPK8 | |
| SCHEMBL5238106 | 0.80 | DPP4 (0.53) | DPP4TACR1 | |
| SCHEMBL5235007 | 0.79 | DPP4 (0.52) | DPP4TACR1KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2007-07-11 | — | — | EP | disclosed |