Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174997 | 0.89 | DPP4 (0.54) | DPP4KCNA5KCNH2TACR1MAPK8 | |
| SCHEMBL5233643 | 0.87 | DPP4 (0.59) | DPP4KCNA5KCNH2TACR1MAPK8 | |
| SCHEMBL5237066 | 0.87 | DPP4 (0.56) | DPP4KCNA5KCNH2TACR1MAPK8 | |
| SCHEMBL5238950 | 0.86 | DPP4 (0.57) | DPP4KCNA5KCNH2MAPTMAPK8 | |
| SCHEMBL5236192 | 0.84 | DPP4 (0.58) | DPP4KCNA5KCNH2MAPTTP53 | |
| SCHEMBL7555668 | 0.83 | DPP4 (0.73) | DPP4KCNA5KCNH2PRKCAGSK3B | |
| SCHEMBL5237562 | 0.83 | DPP4 (0.52) | DPP4MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5237550 | 0.83 | DPP4 (0.52) | DPP4MAPTKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5238032 | 0.83 | DPP4 (0.71) | DPP4KCNA5KCNH2MAPTRXFP1 | |
| SCHEMBL5239049 | 0.81 | GRIA2 (0.48) | DPP4KCNA5KCNH2TACR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2007-07-11 | — | — | EP | disclosed |