Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.54 |
| ▸ | CDK8 | P49336 | 5/20 | 0.54 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.54 |
| ▸ | IKBKB | O14920 | 5/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236328 | 0.88 | ALDH1A1 (0.66) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL5239520 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL427267 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL5235050 | 0.81 | IKBKB (0.61) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL5234359 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL5236613 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL18537598 | 0.79 | ALDH1A1 (0.71) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL4657885 | 0.77 | IKBKB (0.70) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL5236334 | 0.77 | ALDH1A1 (0.69) | ALDH1A1HTTHPGDALOX15TSHR | |
| SCHEMBL16071477 | 0.76 | KDM4E (0.65) | ALDH1A1HTTHPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
| CN-1968954-A | Thienopyridine Derivatives | SANKYO CO (JP) | 2007-05-23 | — | — | CN | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | ALDH1A1 1073/4885HTT 3498/4885HPGD 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.