Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.60 |
| ▸ | CDK8 | P49336 | 9/20 | 0.60 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.60 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234359 | 0.84 | ALDH1A1 (0.60) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL5236613 | 0.84 | ALDH1A1 (0.60) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL5236328 | 0.83 | ALDH1A1 (0.66) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL27702802 | 0.82 | KDM4E (0.61) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL5239520 | 0.82 | ALDH1A1 (0.64) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL27723169 | 0.81 | IKBKB (0.57) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL16071472 | 0.81 | KDM4E (0.62) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL16071477 | 0.81 | KDM4E (0.65) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL5234057 | 0.81 | ALDH1A1 (0.69) | IKBKBALDH1A1KDM4EHTTHPGD | |
| SCHEMBL5236334 | 0.79 | ALDH1A1 (0.69) | IKBKBALDH1A1KDM4EHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | IKBKB 1715/4885ALDH1A1 1073/4885KDM4E 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.