Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11320851 | 0.98 | HTT (0.47) | HTTKMT2AMAPTPKMCASP6 | |
| SCHEMBL13784861 | 0.77 | GAA (0.39) | HTTKMT2AMAPTPKMGAA | |
| SCHEMBL7108756 | 0.74 | HTT (0.45) | HTTKMT2AMAPTCASP6HPGD | |
| SCHEMBL11862074 | 0.74 | HTT (0.45) | HTTKMT2AMAPTCASP6GAA | |
| SCHEMBL5200953 | 0.74 | HTT (0.42) | HTTKMT2AMAPTCASP6GAA | |
| SCHEMBL2467004 | 0.69 | — | — | |
| SCHEMBL34154 | 0.69 | — | — | |
| SCHEMBL5655367 | 0.69 | SMN1; SMN2 (0.68) | HTTKMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL5201246 | 0.69 | MAPT (0.47) | HTTKMT2AMAPTCASP6CDK8 | |
| SCHEMBL9384732 | 0.68 | ADORA1 (0.42) | HTTKMT2AMAPTCDK9CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20070033742-A1 | Pyrazole azomethines and colorants containing these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |
| US-6645258-B2 | Oxidation base selected from a 3-substituted 4,5-diaminopyrazoles; reacting | L'OREAL, S.A. (FR) | 2003-11-11 | — | — | US | disclosed |
| US-20030019051-A9 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | L'OREAL | 2003-01-30 | — | — | US | disclosed |
| US-20020050013-A1 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | L'OREAL | 2002-05-02 | — | — | US | disclosed |
| US-6338741-B1 | 3-SUBSTITUTED 4,5-DIAMINOPYRAZOLES, OXIDATION HAIR DYES, STRONG COLORATION IN SHADES RANGING FROM RED TO BLUE | L'OREAL (FR) | 2002-01-15 | — | — | US | disclosed |
| US-6099592-A | SPECIFIED 3-SUBSTITUTED 4,5-DIAMINOPYRAZOLES SUCH AS 1-BENZYL-4,5-DIAMINO-3-METHYLPYRAZOLE AS OXIDATION DYE PRECURSORS; USE TO OBTAIN DYE COMPOSITIONS LEADING TO STRONG COLORATIONS, IN SHADES RANGING FROM RED TO BLUE | L'OREAL (FR) | 2000-08-08 | — | — | US | disclosed |
| EP-0740931-B1 | Compositions for dyeing keratinic fibers containing diaminopyrazoles, process for dyeing, diaminopyrazoles and process for their preparation | OREAL (FR) | 1997-08-20 | — | — | EP | disclosed |
| EP-0740931-A1 | Compositions for dyeing keratinic fibers containing diaminopyrazoles, process for dyeing, diaminopyrazoles and process for their preparation | L'OREAL (FR) | 1996-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020050013-A1 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | KRT18, DSP, TUBB3 | HTT 4327/4885KMT2A 1275/4885MAPT 186/4885 |
| US-20030019051-A9 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | KRT18, DSP, TUBB3 | HTT 4327/4885KMT2A 1275/4885MAPT 186/4885 |
| US-20070033742-A1 | Pyrazole azomethines and colorants containing these compounds | KRT18, NOX5, TUBB3 | HTT 4670/4885KMT2A 1914/4885MAPT 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.