Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 5/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071426 | 0.83 | HRH3 (0.47) | HRH3KMT2ANAAACHRNB2CHRNA4 | |
| SCHEMBL15358134 | 0.83 | HRH3 (0.47) | HRH3KMT2ANAAACHRNB2CHRNA4 | |
| SCHEMBL6050192 | 0.83 | HRH3 (0.42) | HRH3KMT2ANAAACHRNB2CHRNA4 | |
| SCHEMBL5236369 | 0.82 | CHRNB2 (0.48) | HRH3KMT2ACHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL7422319 | 0.82 | HRH3 (0.46) | HRH3KMT2ANAAACHRNB2CHRNA4 | |
| SCHEMBL2411749 | 0.82 | HRH3 (0.46) | HRH3KMT2ANAAACHRNB2CHRNA4 | |
| SCHEMBL13282815 | 0.81 | HRH3 (0.47) | HRH3KMT2ANAAACHRNB2CHRNA4 | |
| SCHEMBL4303428 | 0.80 | NAAA (0.48) | HRH3KMT2ANAAACHRNB2CHRNA4 | |
| SCHEMBL12557625 | 0.80 | NAAA (0.48) | HRH3KMT2ANAAACHRNB2CHRNA4 | |
| SCHEMBL13285747 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |