Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229947 | 0.93 | TRPM8 (0.32) | NR1H4LMNAKDM4EALDH1A1GLA | |
| SCHEMBL5234966 | 0.93 | TRPM8 (0.32) | NR1H4LMNAKDM4EALDH1A1GLA | |
| SCHEMBL5236173 | 0.89 | CYP17A1 (0.30) | — | |
| SCHEMBL5232278 | 0.89 | NR1H4 (0.34) | NR1H4KDROPRM1MEN1KMT2A | |
| SCHEMBL5232272 | 0.89 | NR1H4 (0.34) | NR1H4KDROPRM1MEN1KMT2A | |
| SCHEMBL5236283 | 0.87 | — | — | |
| SCHEMBL5234535 | 0.87 | — | — | |
| SCHEMBL5233878 | 0.87 | — | — | |
| SCHEMBL5233446 | 0.86 | NPC1 (0.35) | MEN1KMT2ATSHRRAB9AKDM4E | |
| SCHEMBL5233366 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730116-B1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-09-05 | — | — | EP | claimed |