Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237502 | 1.00 | LOXL2 (0.43) | LOXL2CYP1A2CNR2PTGDR2BCHE | |
| SCHEMBL5240093 | 0.87 | CNR2 (0.45) | LOXL2CYP1A2CNR2FLT1KDR | |
| SCHEMBL5231738 | 0.87 | CNR2 (0.45) | LOXL2CYP1A2CNR2FLT1KDR | |
| SCHEMBL5234948 | 0.86 | LOXL2 (0.46) | LOXL2CYP1A2HDAC3ACHEHDAC1 | |
| SCHEMBL5234952 | 0.86 | LOXL2 (0.46) | LOXL2CYP1A2HDAC3ACHEHDAC1 | |
| SCHEMBL5238056 | 0.85 | CYP1A2 (0.54) | LOXL2CYP1A2HDAC3ACHEHDAC1 | |
| SCHEMBL5238727 | 0.85 | CYP1A2 (0.54) | LOXL2CYP1A2HDAC3ACHEHDAC1 | |
| SCHEMBL5235754 | 0.85 | AURKA (0.39) | LOXL2CYP1A2CNR2FLT1KDR | |
| SCHEMBL5235758 | 0.85 | AURKA (0.39) | LOXL2CYP1A2CNR2FLT1KDR | |
| SCHEMBL5238458 | 0.83 | LOXL2 (0.46) | LOXL2CYP1A2FLT1KDRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | disclosed |
| CN-1951939-A | Novel pyrrole derivatives as pharmaceutical agents | LILLY CO ELI (US) | 2007-04-25 | — | — | CN | disclosed |
| CN-1269820-C | Novel pyrrole derivatives as medicaments | LILLY CO ELI (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1511157-A | Novel pyrrole derivatives as medicaments | — | 2004-07-07 | — | — | CN | disclosed |