Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235658 | 1.00 | KMT2A (0.47) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5235665 | 1.00 | KMT2A (0.47) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5234638 | 0.92 | NPC1 (0.50) | KMT2AMEN1CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11610126 | 0.86 | KMT2A (0.49) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5238423 | 0.83 | ALDH1A1 (0.54) | KMT2AMEN1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5238435 | 0.83 | ALDH1A1 (0.54) | KMT2AMEN1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5238428 | 0.83 | ALDH1A1 (0.54) | KMT2AMEN1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3911693 | 0.74 | KMT2A (0.62) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11609036 | 0.74 | KMT2A (0.50) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL5237453 | 0.73 | TSHR (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | KMT2A 2660/4885MEN1 975/4885CYP2D6 2528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.