SCHEMBL5235804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5475253	0.99	VCP (0.50)	VCPMAPKAPK2BRD4JAK2TRPV1
	SCHEMBL16349077	0.89	VCP (0.47)	VCPJAK2TRPV1KDRIMPDH2
	SCHEMBL5477719	0.89	VCP (0.46)	VCPJAK2TRPV1KDRIMPDH2
	SCHEMBL16348971	0.88	VCP (0.48)	VCPJAK2TRPV1KDRIMPDH2
	SCHEMBL5472953	0.88	VCP (0.48)	VCPJAK2TRPV1KDRIMPDH2
	SCHEMBL5481749	0.88	VCP (0.46)	VCPBRD4JAK2TRPV1KDR
	SCHEMBL5227541	0.87	VCP (0.45)	VCPBRD4JAK2KDRIMPDH2
	SCHEMBL5477651	0.86	VCP (0.44)	VCPBRD4JAK2KDRIMPDH2
	SCHEMBL5472158	0.86	VCP (0.67)	VCPMAPKAPK2BRD4JAK2KDR
	SCHEMBL5230752	0.85	VCP (0.43)	VCPBRD4TRPV1KDRIMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.