SCHEMBL5472158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5470454	0.92	VCP (0.69)	VCPMAPKAPK2IMPDH2FLT1FLT4
	SCHEMBL5469457	0.91	VCP (0.68)	VCPMAPKAPK2JAK2IMPDH2FLT1
	SCHEMBL5469448	0.90	BRD4 (0.55)	VCPMAPKAPK2JAK2BRD4IMPDH2
	SCHEMBL5230351	0.89	VCP (0.63)	VCPMAPKAPK2JAK2BRD4IMPDH2
	SCHEMBL5472810	0.89	BRD4 (0.56)	VCPMAPKAPK2JAK2BRD4IMPDH2
	SCHEMBL16348997	0.89	VCP (0.66)	VCPMAPKAPK2JAK2IMPDH2FLT1
	SCHEMBL5184581	0.88	VCP (0.52)	VCPMAPKAPK2JAK2BRD4IMPDH2
	SCHEMBL5465207	0.88	VCP (0.61)	VCPMAPKAPK2JAK2BRD4IMPDH2
	SCHEMBL5464712	0.88	VCP (0.51)	VCPMAPKAPK2JAK2BRD4IMPDH2
	SCHEMBL5475439	0.87	VCP (0.60)	VCPMAPKAPK2JAK2BRD4IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.