SCHEMBL523640

SCHEMBL523640

N#Cc1ccc(Sc2ccccc2)cc1C#N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 1.00
MAOA P21397 11/20 1.00
MCL1 Q07820 1/20 0.56
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
PLA2G1B P04054 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
AR P10275 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13907659 0.89 MAOB (0.80) MAOBMAOAMCL1AR
SCHEMBL3961581 0.85 MAOA (0.73) MAOBMAOAMCL1ALDH1A1KDM4E
SCHEMBL7256911 0.83 MAOA (0.71) MAOBMAOAMCL1ALDH1A1KDM4E
SCHEMBL9174096 0.83 MAOA (0.71) MAOBMAOAMCL1ALDH1A1KDM4E
SCHEMBL22749185 0.82 MAOB (0.70) MAOBMAOAMCL1AR
SCHEMBL12949048 0.82 MAOB (1.00) MAOBMAOAALDH1A1KDM4EMAPT
SCHEMBL30360762 0.82 MAOB (0.70) MAOBMAOAMCL1KDM4EMAPT
SCHEMBL20511089 0.82 MAOB (0.70) MAOBMAOAMCL1KDM4EMAPT
SCHEMBL522618 0.81 MAOB (0.68) MAOBMAOAMCL1KDM4EMAPT
SCHEMBL21878993 0.78 MAOB (0.64) MAOBMAOAMCL1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12129381-B1 Single vessel solvent based method for making a Zn/Cu composite IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-10-29 US disclosed
US-20240336778-A1 SINGLE VESSEL SOLVENT BASED METHOD FOR MAKING A ZN/CU COMPOSITE IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-10-10 US disclosed
US-12031043-B2 Method for synthesizing a micro/nanosphere-containing composite IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-07-09 US disclosed
US-11827792-B2 Wastewater purification composition for organic dyes IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-11-28 US disclosed
US-20230279232-A1 WASTEWATER PURIFICATION COMPOSITION FOR ORGANIC DYES IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-09-07 US disclosed
US-11667793-B2 Photosensitizer composite and uses thereof IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-06-06 US disclosed
US-11661516-B2 Solar light antibactertal agent IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-05-30 US disclosed
US-20230041590-A1 PHOTOSENSITIZER COMPOSITE AND USES THEREOF IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-02-09 US disclosed
US-20230028656-A1 SOLAR LIGHT ANTIBACTERIAL AGENT IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-01-26 US disclosed
US-20230002617-A1 METHOD FOR SYNTHESIZING A MICRO/NANOSPHERE-CONTAINING COMPOSITE IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-01-05 US disclosed
EP-1644336-A1 NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN FIBROGEN, INC. (US) 2006-04-12 EP disclosed
US-20040254215-A1 Adjust concentration of erythropoietin in blood; strokes; antiepileptic agents; liver disorders; antiulcer agents; central nervous system disorders FIBROGEN, INC. 2004-12-16 US disclosed
WO-2004108681-A1 NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENOUS ERYTHROPOIETIN FIBROGEN, INC. (US) 2004-12-16 WO disclosed
US-5703229-A ALUMINUM PHTHALOCYANINE SUBSTITUTED WITH POLYESTER REACTIVE GROUPS; TAGGING THERMOPLASTIC WASTES FOR RECYCLING EASTMAN CHEMICAL COMPANY (US) 1997-12-30 US disclosed
US-5525516-A DISSOLVING NEAR INFRARED FLUORESCING COMPOUNDS EASTMAN CHEMICAL COMPANY (US) 1996-06-11 US disclosed
WO-1996010620-A1 METHOD FOR TAGGING PETROLEUM PRODUCTS EASTMAN CHEMICAL COMPANY (US) 1996-04-11 WO disclosed
US-5461136-A Thermoplastic condensation polymer having copolymerized therein one or more near infrared fluorescing compounds EASTMAN CHEMICAL COMPANY (US) 1995-10-24 US disclosed
US-5397819-A Phthalocyanines, naphthalocyanines, sqarines; detectable when exposed to specified wavelength limits of electromagnetic radiation; recycling of wastes EASTMAN CHEMICAL COMPANY (US) 1995-03-14 US disclosed
US-H477-H Monolayer-forming substituted phthalocyanine compounds and method of preparation thereof UNITED STATES OF AMERICA (US) 1988-06-07 US disclosed
US-4636767-A Mixed semiconductor film device for monitoring gases THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1987-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254215-A1 Adjust concentration of erythropoietin in blood; strokes; antiepileptic agents; liver disorders; antiulcer agents; central nervous system disorders EPOR, HIF1AN, HIF1A MAOB 2718/4885MAOA 3338/4885MCL1 2411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.