SCHEMBL30360762

SCHEMBL30360762

Cc1ccc(Sc2ccc(C#N)c(C#N)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.70
MAOA P21397 10/20 0.70
MCL1 Q07820 1/20 0.59
KDM4E B2RXH2 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
AR P10275 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20511089 1.00 MAOB (0.70) MAOBMAOAMCL1KDM4ECYP1A2
SCHEMBL13907659 0.88 MAOB (0.80) MAOBMAOAMCL1AR
SCHEMBL523640 0.82 MAOB (1.00) MAOBMAOAMCL1KDM4ECYP1A2
SCHEMBL22749185 0.81 MAOB (0.70) MAOBMAOAMCL1AR
SCHEMBL12949048 0.81 MAOB (1.00) MAOBMAOAKDM4ECYP1A2CYP3A4
SCHEMBL21878993 0.80 MAOB (0.64) MAOBMAOAMCL1AR
SCHEMBL30360771 0.80 MAOB (0.64) MAOBMAOAMCL1AR
SCHEMBL522618 0.79 MAOB (0.68) MAOBMAOAMCL1KDM4EMAPT
SCHEMBL1003862 0.77 ALDH1A1 (0.46) MAOBMAOAKDM4EAR
Water SCHEMBL27795471 0.76 TDP1 (0.53) MCL1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461814-B Resin blends, prepregs and articles containing a phthalonitrile reactive diluent and a bisphthalonitrile resin 3M创新有限公司 2023-04-14 CN disclosed