SCHEMBL523645

SCHEMBL523645

CCC(c1c(F)c(F)c(F)c(F)c1F)[Si](C)(C)Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL523413 0.84 PKM (0.31) PKMSMN1; SMN2
SCHEMBL209860 0.71
SCHEMBL209770 0.70
SCHEMBL28390192 0.69
SCHEMBL16294126 0.65
SCHEMBL14308037 0.64 PKM (0.32) PKMSMN1; SMN2
SCHEMBL18549763 0.62
SCHEMBL107647 0.62 PKM (0.35) PKMSMN1; SMN2
SCHEMBL3149258 0.62
SCHEMBL22598355 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025027609-A1 SYSTEMS AND METHODS FOR ELECTROCHEMICAL DETECTION OF DRUGS IN GASEOUS SAMPLES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2025-02-06 WO disclosed
US-10877041-B2 Methods of detecting biological prints, fluids or analytes therein using porous semiconductor substrates VOELCKER, Nicolas H. 2020-12-29 US disclosed
US-10816556-B2 Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry THE GEORGE WASHINGTON UNIVERSITY (US) 2020-10-27 US disclosed
US-20200292557-A1 TAILORED NANOPOST ARRAYS (NAPA) FOR LASER DESORPTION IONIZATION IN MASS SPECTROMETRY UT-BATTELLE, LLC 2020-09-17 US disclosed
EP-3152582-B1 METHODS OF DETECTING BIOLOGICAL PRINTS, FLUIDS OR ANALYTES THEREIN USING POROUS SEMICONDUCTOR SUBSTRATES VOELCKER NICOLAS HANS (AU) 2020-06-24 EP disclosed
US-10585104-B2 Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry THE GEORGE WASHINGTON UNIVERSITY (US) 2020-03-10 US disclosed
US-20170227546-A1 TAILORED NANOPOST ARRAYS (NAPA) FOR LASER DESORPTION IOINZATION IN MASS SPECTROMETRY THE GEORGE WASHINGTON UNIVERSITY 2017-08-10 US disclosed
US-20170107413-A1 Anti-icing composition driven by catalytic hydrogen generation under subzero temperatures WANG LIANG (US) 2017-04-20 US disclosed
EP-3152582-A1 METHODS OF DETECTING BIOLOGICAL PRINTS, FLUIDS OR ANALYTES THEREIN USING POROUS SEMICONDUCTOR SUBSTRATES Voelcker, Nico (AU) 2017-04-12 EP disclosed
US-20170074885-A1 METHODS OF DETECTING BIOLOGICAL PRINTS, FLUIDS OR ANALYTES THEREIN USING POROUS SEMICONDUCTOR SUBSTRATES UNIVERSITY OF SOUTH AUSTRALIA (AU) 2017-03-16 US disclosed
US-20060159916-A1 Suppression of biofilm production; semiconductors NANOSYS, INC. (US) 2006-07-20 US disclosed
US-20060110351-A1 Use of silanes on cosmetic agents and methods for treating hair ITN NANOVATION AG (DE) 2006-05-25 US disclosed
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance CHISSO CORPORATION (JP) 2006-03-09 US disclosed
EP-1620256-A2 NANOFIBER SURFACES FOR USE IN ENHANCED SURFACE AREA APPLICATIONS Nanosys, Inc. (US) 2006-02-01 EP disclosed
EP-1555990-A1 USE OF SILANES IN COSMETIC AGENTS AND METHODS FOR TREATING HAIR ITN NANOVATION GMBH (DE) 2005-07-27 EP disclosed
WO-2005034205-A2 SELF ASSEMBLING NANOPARTICLE-POLYMER HYBRIDS DOW CORNING CORPORATION (US) 2005-04-14 WO disclosed
WO-2004099068-A2 NANOFIBER SURFACES FOR USE IN ENHANCED SURFACE AREA APPLICATIONS NANOSYS, INC. (US) 2004-11-18 WO disclosed
US-6746608-B2 LYSIS OF PLASMIDS WITH FLUOROPOLYMER; LIQUID CHROMATOGRAPHY PROMETIC BIOSCIENCES, INC. (CA) 2004-06-08 US disclosed
WO-2004012691-A1 USE OF SILANES IN COSMETIC AGENTS AND METHODS FOR TREATING HAIR ITN NANOVATION GMBH (DE) 2004-02-12 WO disclosed
US-20030162853-A1 Use of adsorbent polymer particles in DNA separation PROMETIC BIOSCIENCES LTD. (GB) 2003-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance STS, PFAS, POLQ PKM 2722/4885SMN1; SMN2 4297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.