Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.44 |
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332133 | 0.85 | TDP1 (0.64) | MEN1KMT2ATDP1MTNR1AMTNR1B | |
| SCHEMBL3581821 | 0.85 | TDP1 (0.64) | MEN1KMT2ATDP1MTNR1AMTNR1B | |
| SCHEMBL9711167 | 0.84 | MEN1 (0.47) | MEN1KMT2ATDP1MTNR1AMTNR1B | |
| SCHEMBL18015817 | 0.81 | CYP2A6 (0.43) | MEN1KMT2AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL27366928 | 0.81 | MAPT (0.48) | MEN1KMT2ATDP1 | |
| SCHEMBL5235807 | 0.81 | TDP1 (0.45) | MEN1KMT2ATDP1MTNR1AMTNR1B | |
| SCHEMBL28843867 | 0.79 | NQO2 (0.50) | MEN1KMT2ATDP1MTNR1AMTNR1B | |
| SCHEMBL30716622 | 0.79 | TDP1 (0.69) | MEN1KMT2ATDP1CYP1A2CYP2C19 | |
| SCHEMBL266575 | 0.79 | TDP1 (0.69) | MEN1KMT2ATDP1CYP1A2CYP2C19 | |
| SCHEMBL9711171 | 0.79 | MEN1 (0.45) | MEN1KMT2ATDP1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |