SCHEMBL27366928

SCHEMBL27366928

CCOC(=O)Cc1cccc2ccc(Cl)cc12

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.48
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 4/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
HPGD P15428 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
LMNA P02545 3/20 0.46
AHR P35869 1/20 0.46
POLB P06746 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
GAA P10253 2/20 0.44
MAOB P27338 1/20 0.44
GLA P06280 1/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15305557 0.86 L3MBTL1 (0.50) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL15747695 0.84 KDM4E (0.55) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL27367110 0.83 HPGD (0.56) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL4752950 0.82 MTNR1A (0.59) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL845701 0.82 KMT2A (0.62) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL29729685 0.82 KMT2A (0.62) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL5236753 0.81 MEN1 (0.47) TDP1KMT2AMEN1
SCHEMBL28332298 0.80 KMT2A (0.53) MAPTALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL31332133 0.79 TDP1 (0.64) TDP1KMT2AMEN1
SCHEMBL3581821 0.79 TDP1 (0.64) TDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 MAPT 224/4885ALDH1A1 359/4885KDM4E 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.