Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355109 | 0.93 | ADAMTS4 (0.36) | MMEADAMTS4ANPEPERAP1HTT | |
| SCHEMBL23752491 | 0.81 | ANPEP (0.41) | ADAMTS4ANPEPERAP1 | |
| SCHEMBL2353264 | 0.81 | ANPEP (0.41) | ADAMTS4ANPEPERAP1 | |
| SCHEMBL23752492 | 0.81 | ANPEP (0.41) | ADAMTS4ANPEPERAP1 | |
| SCHEMBL2353188 | 0.80 | ADAMTS4 (0.40) | ADAMTS4ANPEPERAP1 | |
| SCHEMBL2350989 | 0.79 | CPB2 (0.42) | ADAMTS4ANPEPERAP1 | |
| SCHEMBL2357292 | 0.79 | CPB2 (0.42) | ADAMTS4ANPEPERAP1 | |
| SCHEMBL6130893 | 0.79 | CPB2 (0.42) | ADAMTS4ANPEPERAP1 | |
| SCHEMBL2356327 | 0.79 | CPB2 (0.42) | ADAMTS4ANPEPERAP1 | |
| SCHEMBL2349012 | 0.79 | CPB2 (0.42) | ADAMTS4ANPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817041-A2 | TAFI INHIBITORS AND THEIR USE TO TREAT PULMONARY FIBROSIS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006041808-A2 | TAFI INHIBITORS AND THEIR USE TO TREAT PULMONARY FIBROSIS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-04-20 | — | — | WO | disclosed |