Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233007 | 0.91 | CYP1A2 (0.42) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL2125547 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL5236476 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL8035089 | 0.78 | HSD17B10 (0.46) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL5233831 | 0.77 | HPGD (0.43) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL2369777 | 0.77 | KDM4E (0.47) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL1913995 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL8988212 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL11140752 | 0.75 | NCEH1 (0.50) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL16260132 | 0.75 | KDM4E (0.59) | ALDH1A1KDM4EHPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |