Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232032 | 0.97 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 | |
| Hydrochloric Acid SCHEMBL27414981 | 0.91 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 | |
| SCHEMBL5234710 | 0.87 | NAAA (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 | |
| SCHEMBL1839983 | 0.85 | NAAA (0.46) | CPN1CPB2LMNAAPOBEC3AAPOBEC3G | |
| SCHEMBL5237250 | 0.85 | KMT2A (0.43) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 | |
| SCHEMBL27271782 | 0.84 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 | |
| SCHEMBL27271788 | 0.84 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 | |
| Hydrochloric Acid SCHEMBL28750161 | 0.83 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 | |
| SCHEMBL29068162 | 0.81 | KMT2A (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 | |
| SCHEMBL9732440 | 0.81 | KMT2A (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3CPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1968954-A | Thienopyridine Derivatives | SANKYO CO (JP) | 2007-05-23 | — | — | CN | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |