SCHEMBL52379

SCHEMBL52379

CCCC[C@H](N)C(=O)OC(=O)[C@H](N)CCCN

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 8/20 0.51
DPP9 Q86TI2 6/20 0.51
DPP8 Q6V1X1 5/20 0.51
DPP4 P27487 3/20 0.51
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
SLC15A1 P46059 1/20 0.44
GSR P00390 1/20 0.44
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
RRM1 P23921 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
METAP1 P53582 1/20 0.40
TLR2 O60603 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1484685 0.94 GNAI3 (0.53) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL5497695 0.92 DPP7 (0.50) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL21114423 0.92 DPP7 (0.50) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL6445484 0.92 DPP7 (0.50) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL997560 0.90 GSR (0.52) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL29075853 0.90 GSR (0.52) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL1537223 0.90 GSR (0.52) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL28782508 0.89 GSR (0.44) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL680614 0.86 GSR (0.59) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL2029834 0.85 GSR (0.44) DPP7DPP9DPP8DPP4GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037593-B2 Methods and means for modifying the alkaloid content of plants BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2024-07-16 US disclosed
EP-3500670-B1 METHOD FOR SELECTING TARGET SEQUENCES FOR GUIDE RNA OF CRISPR SYSTEMS BROAD INST INC (US) 2024-07-10 EP disclosed
EP-3500671-B1 METHOD OF SELECTING TARGET SEQUENCES FOR THE DESIGN OF GUIDE RNAS BROAD INST INC (US) 2024-07-10 EP disclosed
CN-113355307-B Proteins 国际N&H丹麦有限公司 2024-07-05 CN disclosed
WO-2024145191-A2 METHODS FOR PRODUCING PLANT BASED FOOD ALTERNATIVES INTERNATIONAL N&H DENMARK APS (DK) 2024-07-04 WO disclosed
US-12023391-B2 Alpha(v)beta(6) integrin-binding peptides and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-02 US disclosed
US-20240209359-A1 METHODS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FOR CAS ENZYMES OR CRISPR-CAS SYSTEMS FOR TARGET SEQUENCES AND CONVEYING RESULTS THEREOF THE BROAD INSTITUTE, INC. (US) 2024-06-27 US disclosed
US-12018275-B2 Delivery and use of the CRISPR-CAS systems, vectors and compositions for hepatic targeting and therapy THE BROAD INSTITUTE, INC. (US) 2024-06-25 US disclosed
US-20240191223-A1 TYPE VI CRISPR ORTHOLOGS AND SYSTEMS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-06-13 US disclosed
US-20240180172-A1 AMYLASE POLYPEPTIDES WITH IMPROVED PROPERTIES DUPONT NUTRITION BIOSCI APS (DK) 2024-06-06 US disclosed
WO-2001077380-A2 METHOD FOR PREDICTING PREDISPOSITION TO A DISEASE ASSOCIATED WITH MUTATIONS IN A RPGR GENE MEDICAL RESEARCH COUNCIL (GB) 2001-10-18 WO disclosed
EP-1135410-A2 ANTENNAPEDIA HOMEODOMAIN HELIX 3 DERIVED TRANSLOCATION VECTORS Cyclacel Limited (GB) 2001-09-26 EP disclosed
EP-1118858-A2 Assay method Pfizer Limited (GB) 2001-07-25 EP disclosed
EP-1108360-A1 Method of improving dough and bread quality DANISCO A/S (DK) 2001-06-20 EP disclosed
WO-2001039602-A1 METHOD OF IMPROVING DOUGH AND BREAD QUALITY DANISCO A/S (DK) 2001-06-07 WO disclosed
EP-1097718-A1 NPY antagonists for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097719-A1 NEP inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097706-A1 Phosphodiesterase inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097707-A1 Treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
WO-2000029427-A2 ANTENNAPEDIA HOMEODOMAIN HELIX 3 DERIVED TRANSLOCATION VECTORS CYCLACEL LIMITED (GB) 2000-05-25 WO disclosed