SCHEMBL680614

SCHEMBL680614

NCCCC[C@H](N)C(=O)OC(=O)[C@H](N)CCCN

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.59
GNAI3 P08754 1/20 0.42
GNAO1 P09471 1/20 0.42
GNAI1 P63096 1/20 0.42
RNPEP Q9H4A4 1/20 0.42
DPP7 Q9UHL4 9/20 0.41
DPP8 Q6V1X1 4/20 0.41
DPP9 Q86TI2 4/20 0.41
DPP4 P27487 3/20 0.41
CPB2 Q96IY4 4/20 0.41
FAP Q12884 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20240364 0.98 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
SCHEMBL344574 0.98 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
SCHEMBL1404247 0.98 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
Hydrochloric Acid SCHEMBL3825519 0.96 GSR (0.59) GSRGNAI3GNAO1GNAI1RNPEP
Hydrochloric Acid SCHEMBL2099474 0.96 GSR (0.59) GSRGNAI3GNAO1GNAI1RNPEP
SCHEMBL29075853 0.96 GSR (0.52) GSRGNAI3GNAO1GNAI1RNPEP
SCHEMBL1537223 0.96 GSR (0.52) GSRGNAI3GNAO1GNAI1RNPEP
SCHEMBL997560 0.96 GSR (0.52) GSRGNAI3GNAO1GNAI1RNPEP
Hydrochloric Acid SCHEMBL11287494 0.94 GSR (0.57) GSRGNAI3GNAO1GNAI1RNPEP
Hydrochloric Acid SCHEMBL11287492 0.94 GSR (0.57) GSRGNAI3GNAO1GNAI1RNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117925458-A Bacillus BJ-1 for degrading lignin and preparation method of bacillus BJ-1 microbial inoculum thereof 中国科学院东北地理与农业生态研究所 2024-04-26 CN disclosed
US-20240034753-A1 THERAPEUTIC PEPTIDES COHBAR, INC. 2024-02-01 US disclosed
US-20230372434-A1 METHOD OF TREATING FIBROSIS WITH A COMBINATION THERAPY COHBAR, INC. 2023-11-23 US disclosed
WO-2023173174-A1 TARGETED DELIVERY OF THERANOSTIC AGENTS PETER MACCALLUM CANCER INSTITUTE (AU) 2023-09-21 WO disclosed
US-11753445-B2 Therapeutic peptides COHBAR, INC. (US) 2023-09-12 US disclosed
US-20230241241-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-08-03 US disclosed
US-20230218710-A1 METHOD OF TREATING CORONAVIRUS INFECTIONS COHBAR, INC. 2023-07-13 US disclosed
US-20230137562-A1 TAU AGGREGATION INHIBITORS ADRX, INC. 2023-05-04 US disclosed
EP-4168009-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS Hangzhou DAC Biotech Co., Ltd. (CN) 2023-04-26 EP disclosed
EP-4135738-A2 METHOD OF TREATING CORONAVIRUS INFECTIONS Cohbar Inc. (US) 2023-02-22 EP disclosed
EP-1807118-A2 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS Hollis-Eden Pharmaceuticals Inc. (US) 2007-07-18 EP disclosed
WO-2007060409-A1 L-ALANINE DERIVATIVES ASTRAZENECA AB (SE) 2007-05-31 WO disclosed
WO-2007056362-A2 GLUCAGON ANALOGS EXHIBITING PHYSIOLOGICAL SOLUBILITY AND STABILITY INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2007-05-18 WO disclosed
US-20070077201-A1 Stem cell expansion and uses BIOVIE INC. 2007-04-05 US disclosed
US-20070014719-A1 Steroid analogs and characterization and treatment methods BIOVIE INC. 2007-01-18 US disclosed
WO-2006129859-A2 COMBINATIONS OF A SQUALENE SYNTHASE INHIBITOR AND A HMG-COA REDUCTASE INHIBITOR FOR TREATING HYPERLIPIDEMIA TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-12-07 WO disclosed
WO-2006110172-A2 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS HOLLIS-EDEN PHARMACEUTICALS.INC. (US) 2006-10-19 WO disclosed
EP-1650201-A1 BENZOXAZEPINE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2006-04-26 EP disclosed
WO-2004076425-A1 IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS CARNEGIE MELLON UNIVERSITY (US) 2004-09-10 WO disclosed
US-3960658-A RAPID IDENTIFICATION OF UROPATHOGENIC BACTERIA CENTAUR CHEMICAL CO. (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372434-A1 METHOD OF TREATING FIBROSIS WITH A COMBINATION THERAPY MMP1, MMP8, COL2A1 GSR 635/4885GNAI3 4153/4885GNAO1 4386/4885
US-20070014719-A1 Steroid analogs and characterization and treatment methods CYP17A1, HSD17B11, HSD3B1 GSR 1076/4885GNAI3 1921/4885GNAO1 2107/4885
US-20070077201-A1 Stem cell expansion and uses NES, CD44, FGF2 GSR 2775/4885GNAI3 2584/4885GNAO1 3822/4885
US-20230241241-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS CD4, DCLRE1A, TOP1 GSR 4259/4885GNAI3 969/4885GNAO1 1047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.