SCHEMBL5238461

SCHEMBL5238461

[CH2]CC(=O)OCCCCCCCCCCCCCCCC

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.69
RAD52 P43351 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
DGKA P23743 1/20 0.57
TSHR P16473 3/20 0.57
FAAH O00519 2/20 0.56
HTR2C P28335 1/20 0.55
EPHX1 P07099 1/20 0.53
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53
PRSS3 P35030 1/20 0.53
HCAR2 Q8TDS4 1/20 0.48
DNM1 Q05193 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
ACHE P22303 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4371067 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL8378848 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL1717045 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL5236604 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL8390520 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL4369312 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL8379402 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL998571 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL5239460 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR
SCHEMBL697993 1.00 NAAA (0.69) NAAARAD52NPSR1DGKATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448895-B1 CONTINUOUS METHOD FOR THE HYDROGENATION OF AROMATIC COMPOUNDS AET GROUP (FR) 2013-05-01 EP claimed
US-20120172632-A1 CONTINUOUS METHOD FOR THE HYDROGENATION OF AROMATIC COMPOUNDS AET GROUP (FR) 2012-07-05 US claimed
US-20120172632-A1 CONTINUOUS METHOD FOR THE HYDROGENATION OF AROMATIC COMPOUNDS AET GROUP (FR) 2012-07-05 US disclosed
EP-1829678-A1 Resin plate SUMITOMO CHEMICAL CO., LTD. (JP) 2007-09-05 EP disclosed
US-7226970-B2 comprises 2-(1-arylalkylidene) acetic ester and methyl methacrylate/styrene homopolymers/copolymers; for production of light guides; colorless; radiation transparent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-05 US disclosed
US-20060051704-A1 Resin plate SUMITOMO CHEMICAL COMPANY, LIMITED 2006-03-09 US disclosed
US-20040191550-A1 Resin plate SUMITOMO CHEMICAL COMPANY, LIMITED 2004-09-30 US disclosed
US-20040192854-A1 Resin composition and molded article thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2004-09-30 US disclosed
US-6723772-B2 CONTAINING AN ULTRAVIOLET ABSORBER SELECTED FROM THE GROUP CONSISTING OF 2-(1-ARYLALKYLIDENE) MALONATES AND OXALANILIDES; LAMINATED PLATE USED AS A LIGHTING COVER, LIGHT DIFFUSING PLATE FOR LIQUID CRYSTAL DISPLAYS, ETC. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-20 US disclosed
US-20030228481-A1 Laminated resin plate SUMITOMO CHEMICAL COMPANY, LIMITED 2003-12-11 US disclosed
US-20030088001-A1 Resin composition, molded article and laminated plate using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-08 US disclosed
US-6433044-B1 SUPERIOR DURABILITY WITHOUT IMPAIRING TRANSPARENCY; CONTAINING A 2-(1-ARYLALKYLIDENE) MALONIC ACID ESTER PHOTOSTABILIZER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-13 US disclosed
US-20020032285-A1 Methyl methacrylate resin composition and molded article thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2002-03-14 US disclosed
US-5986042-A Cross-linked polymer MITSUI CHEMICALS, INC. (JP) 1999-11-16 US disclosed
EP-0703210-B1 Process for producing 2,6-di-tert-alkylcyclohexanol FUJI PHOTO FILM CO LTD (JP) 1999-03-31 EP disclosed
EP-0856539-A1 Cross-linked polymer Mitsui Chemicals, Inc. (JP) 1998-08-05 EP disclosed
US-5670563-A ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND CIBA-SPECIALTY CHEMICALS CORPORATION (US) 1997-09-23 US disclosed
EP-0703210-A1 Process for producing 2,6-di-tert-alkylcyclohexanol FUJI PHOTO FILM CO., LTD. (JP) 1996-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172632-A1 CONTINUOUS METHOD FOR THE HYDROGENATION OF AROMATIC COMPOUNDS HRH4, CRH, HRH2 NAAA 2266/4885RAD52 4231/4885NPSR1 893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.