Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 3/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5239739 | 0.87 | HPGD (0.39) | HPGDNLRP1PLK1AVPR1BCNR2 | |
| SCHEMBL5238212 | 0.87 | RXFP1 (0.34) | CNR2TP53ALDH1A1GAAMAPT | |
| SCHEMBL5235009 | 0.86 | DPP4 (0.38) | ALDH1A1 | |
| SCHEMBL5236293 | 0.85 | ALDH1A1 (0.41) | HPGDCNR2TP53KDM4EALDH1A1 | |
| SCHEMBL6704499 | 0.85 | PTGER4 (0.33) | AVPR1BCNR2 | |
| SCHEMBL6107675 | 0.84 | HPGD (0.35) | HPGDNLRP1PLK1AVPR1BCNR2 | |
| SCHEMBL6703529 | 0.83 | DPP4 (0.35) | KDM4EKMT2A | |
| SCHEMBL5238488 | 0.82 | HPGD (0.37) | HPGDNLRP1PLK1AVPR1BCNR2 | |
| SCHEMBL5234470 | 0.81 | THRA (0.36) | HPGDCNR2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5236977 | 0.81 | SMN1; SMN2 (0.34) | HPGDCNR2KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2007-07-11 | — | — | EP | disclosed |