SCHEMBL523917

SCHEMBL523917

CCC(CC)COC(=O)[C@H](C)NP(=O)(Cl)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 10/20 0.45
ANPEP P15144 1/20 0.39
LAP3 P28838 1/20 0.39
ELANE P08246 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PRTN3 P24158 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL523916 1.00 BTN3A1 (0.45) BTN3A1ANPEPLAP3ELANEMEN1
SCHEMBL12900849 0.90 BTN3A1 (0.43) BTN3A1ANPEPLAP3ELANEPRTN3
SCHEMBL13469571 0.88 BTN3A1 (0.47) BTN3A1ANPEPLAP3ELANEMEN1
SCHEMBL16258589 0.88 BTN3A1 (0.47) BTN3A1ELANEMEN1KMT2ANPSR1
SCHEMBL23992573 0.87 BTN3A1 (0.57) BTN3A1ANPEPLAP3ELANEMEN1
SCHEMBL14466574 0.87 BTN3A1 (0.57) BTN3A1ANPEPLAP3ELANEMEN1
SCHEMBL807682 0.87 BTN3A1 (0.57) BTN3A1ANPEPLAP3ELANEMEN1
SCHEMBL21158533 0.87 BTN3A1 (0.57) BTN3A1ANPEPLAP3ELANEMEN1
SCHEMBL19504115 0.86 BTN3A1 (0.46) BTN3A1ANPEPLAP3ELANEMEN1
SCHEMBL18666933 0.86 BTN3A1 (0.46) BTN3A1ANPEPLAP3ELANEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11612614-B2 Isomorphs of Remdesivir and methods for synthesis of same Anzalp Pharmasolutions Pvt. Ltd. (IN) 2023-03-28 US claimed
US-12509466-B2 Methods and compounds for treating paramyxoviridae virus infections GILEAD SCIENCES, INC. (US) 2025-12-30 US disclosed
EP-4591935-A2 METHODS FOR THE PREPARATION OF RIBOSIDES Gilead Sciences, Inc. (US) 2025-07-30 EP disclosed
EP-4588928-A2 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS Gilead Sciences, Inc. (US) 2025-07-23 EP disclosed
EP-4036099-B1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES INC (US) 2025-03-19 EP disclosed
CN-119613475-A Preparation method of copper-catalyzed asymmetric synthesis nucleoside prodrug intermediate or prodrug based on P (V) precursor 上海交通大学 2025-03-14 CN disclosed
CN-112513061-B 4' -Thio-nucleotides and-nucleoside prodrugs for treating cancer 南方研究院 2025-01-24 CN disclosed
US-20230381761-A1 CATALYSTS AND THEIR USES IN ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF REMDESIVIR ACADEMIA SINICA (TW) 2023-11-30 US disclosed
US-20230381761-A1 CATALYSTS AND THEIR USES IN ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF REMDESIVIR ACADEMIA SINICA (TW) 2023-11-30 US disclosed
US-11773126-B2 Substituted nucleosides, nucleotides and analogs thereof Janssen Pharmaceuticals, Inc. (US) 2023-10-03 US disclosed
EP-2616080-A1 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT Gilead Sciences, Inc. (US) 2013-07-24 EP disclosed
US-20120107274-A1 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-05-03 US disclosed
US-20120107274-A1 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-05-03 US disclosed
US-20120107274-A1 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-05-03 US disclosed
WO-2012037038-A1 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-03-22 WO disclosed
WO-2012037038-A1 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-03-22 WO disclosed
US-20120027752-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2012-02-02 US disclosed
US-20120027752-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2012-02-02 US disclosed
US-20120027752-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2012-02-02 US disclosed
WO-2012012776-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2012-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120107274-A1 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT PNP, NUDT1, SLC29A2 BTN3A1 3745/4885ANPEP 756/4885LAP3 3872/4885
US-20120027752-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS PNP, RPIA, HPRT1 BTN3A1 4281/4885ANPEP 446/4885LAP3 3407/4885
US-11612614-B2 Isomorphs of Remdesivir and methods for synthesis of same MTAP, SARS1, PNP BTN3A1 4151/4885ANPEP 273/4885LAP3 1518/4885
US-12509466-B2 Methods and compounds for treating paramyxoviridae virus infections MTAP, PNP, NSUN2 BTN3A1 4120/4885ANPEP 1420/4885LAP3 3486/4885
US-11773126-B2 Substituted nucleosides, nucleotides and analogs thereof PNP, TYMP, SLC29A1 BTN3A1 4290/4885ANPEP 278/4885LAP3 2623/4885
US-20230381761-A1 CATALYSTS AND THEIR USES IN ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF REMDESIVIR MTAP, PNP, ALKBH1 BTN3A1 4593/4885ANPEP 171/4885LAP3 1121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.