Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240138 | 0.89 | KMT2A (0.46) | DAOL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL3594395 | 0.83 | TDP1 (0.56) | FFAR1DAOKMT2AMEN1GAA | |
| SCHEMBL5237113 | 0.82 | KMT2A (0.41) | L3MBTL1KMT2AMEN1MAPTLMNA | |
| SCHEMBL11462750 | 0.81 | KDM4E (0.46) | FFAR1DAOL3MBTL1KMT2AMEN1 | |
| SCHEMBL6411595 | 0.80 | RIPK1 (0.42) | FFAR1DAOKMT2AMEN1MAPT | |
| SCHEMBL18791620 | 0.79 | CYP1A2 (0.50) | DAOL3MBTL1MAPTLMNAPOLB | |
| SCHEMBL8429673 | 0.78 | DAO (0.46) | FFAR1DAOMAPTLMNACNR1 | |
| SCHEMBL5233214 | 0.78 | CYP1A2 (0.48) | L3MBTL1KMT2AMEN1MAPTLMNA | |
| SCHEMBL28905013 | 0.78 | RXFP1 (0.50) | L3MBTL1KMT2AMEN1MAPTLMNA | |
| Acetic Acid SCHEMBL31618213 | 0.77 | TAAR1 (0.44) | FFAR1DAOMAPTNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112479998-B | Dihydroquinoline fluorescent probe and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2022-03-15 | — | — | CN | disclosed |
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |