Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235068 | 0.83 | IAPP (0.46) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL5240138 | 0.82 | KMT2A (0.46) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL5239308 | 0.82 | FFAR1 (0.41) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL5234763 | 0.76 | NOTUM (0.39) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL23365341 | 0.76 | TDP1 (0.36) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL11205828 | 0.74 | RIPK1 (0.46) | KMT2AMEN1CES2CES1L3MBTL1 | |
| SCHEMBL6046939 | 0.74 | KMT2A (0.57) | KMT2AMEN1MAPTPOLBTDP1 | |
| SCHEMBL125583 | 0.74 | ALDH1A1 (0.49) | LMNARAB9ANPC1NOD2L3MBTL1 | |
| SCHEMBL9102212 | 0.73 | P2RX7 (0.45) | KMT2AMEN1RAB9ANPC1CES2 | |
| SCHEMBL28357376 | 0.73 | ANO1 (0.47) | KMT2AMEN1CES2CES1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |