Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.73 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.58 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239063 | 0.91 | AVPR2 (0.60) | AVPR2AVPR1A | |
| SCHEMBL5236665 | 0.89 | AVPR2 (0.58) | AVPR2AVPR1AOXTR | |
| SCHEMBL5239551 | 0.88 | AVPR2 (0.67) | AVPR2AVPR1A | |
| SCHEMBL5235967 | 0.85 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL5235980 | 0.84 | AVPR2 (1.00) | AVPR2AVPR1A | |
| SCHEMBL5238090 | 0.83 | AVPR2 (0.57) | AVPR2AVPR1A | |
| SCHEMBL27473847 | 0.83 | AVPR2 (0.67) | AVPR2AVPR1A | |
| SCHEMBL7335574 | 0.80 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL5320547 | 0.79 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL7308396 | 0.78 | AVPR2 (0.54) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022295-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| EP-0804440-B1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2007-12-19 | — | — | EP | disclosed |
| US-5532235-A | TO TREAT EXCESS RENAL REABSORPTION | AMERICAN CYANAMID COMPANY (US) | 1996-07-02 | — | — | US | disclosed |