Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239551 | 0.91 | AVPR2 (0.67) | AVPR2AVPR1A | |
| SCHEMBL7335574 | 0.89 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL5239063 | 0.89 | AVPR2 (0.60) | AVPR2AVPR1A | |
| SCHEMBL7308396 | 0.84 | AVPR2 (0.54) | AVPR2AVPR1A | |
| SCHEMBL7319146 | 0.83 | AVPR2 (0.48) | AVPR2AVPR1ACRBN | |
| SCHEMBL5231105 | 0.82 | AVPR2 (0.82) | AVPR2AVPR1A | |
| SCHEMBL7334536 | 0.79 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL5239585 | 0.79 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL7337329 | 0.75 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL7369779 | 0.75 | AVPR2 (0.57) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022295-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| EP-0804440-B1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2007-12-19 | — | — | EP | disclosed |
| US-5532235-A | TO TREAT EXCESS RENAL REABSORPTION | AMERICAN CYANAMID COMPANY (US) | 1996-07-02 | — | — | US | disclosed |