Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.51 |
| ▸ | OXTR | P30559 | 4/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239551 | 0.89 | AVPR2 (0.67) | AVPR2AVPR1A | |
| SCHEMBL5236665 | 0.89 | AVPR2 (0.58) | AVPR2AVPR1AOXTR | |
| SCHEMBL9065667 | 0.87 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL5320547 | 0.84 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL5233202 | 0.81 | AVPR2 (0.81) | AVPR2AVPR1AOXTR | |
| SCHEMBL5239585 | 0.78 | AVPR2 (0.73) | AVPR2AVPR1AOXTR | |
| SCHEMBL7336311 | 0.77 | AVPR2 (0.60) | AVPR2AVPR1AOXTR | |
| SCHEMBL8408815 | 0.76 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL9059943 | 0.75 | AVPR2 (0.75) | AVPR2AVPR1A | |
| SCHEMBL8818713 | 0.75 | AVPR2 (0.58) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022295-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| US-5532235-A | TO TREAT EXCESS RENAL REABSORPTION | AMERICAN CYANAMID COMPANY (US) | 1996-07-02 | — | — | US | disclosed |