Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.61 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | UBE2N | P61088 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620366 | 1.00 | POLB (0.72) | POLBNPC1RAB9ADDAH1RAD52 | |
| Hydrochloric Acid SCHEMBL2454024 | 0.98 | POLB (0.70) | POLBNPC1RAB9ADDAH1RAD52 | |
| Hydrochloric Acid SCHEMBL28373229 | 0.98 | POLB (0.70) | POLBNPC1RAB9ADDAH1RAD52 | |
| Hydrochloric Acid SCHEMBL7413158 | 0.96 | POLB (0.68) | POLBNPC1RAB9ADDAH1RAD52 | |
| SCHEMBL29505763 | 0.89 | POLB (0.79) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL856769 | 0.89 | POLB (0.79) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL230157 | 0.88 | POLB (0.84) | POLBNPC1RAB9ADDAH1CHRM1 | |
| Hydrochloric Acid SCHEMBL8327038 | 0.87 | POLB (0.77) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL1884524 | 0.87 | POLB (0.83) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL4704495 | 0.86 | POLB (0.80) | POLBNPC1RAB9ADDAH1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |
| EP-2546387-A1 | Adhesion promotion of metal to laminate with a multi-functional compound | Enthone, Inc. (US) | 2013-01-16 | — | — | EP | claimed |
| EP-1732896-B1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMA INC (US) | 2012-12-12 | — | — | EP | claimed |
| EP-2274460-B1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND | ENTHONE (US) | 2012-10-10 | — | — | EP | claimed |
| US-20120202795-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2012-08-09 | — | — | US | claimed |
| US-20120168075-A1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH MULTI-FUNCTIONAL MOLECULAR SYSTEM | ENTHONE INC. (US) | 2012-07-05 | — | — | US | claimed |
| EP-2274460-A1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND HAFTFORDERUNG VON METALL ZU LAMINATEN MIT EINER MULTIFUNKTIONELLEN | Enthone, Inc. (US) | 2011-01-19 | — | — | EP | claimed |
| WO-2009117734-A1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND HAFTFORDERUNG VON METALL ZU LAMINATEN MIT EINER MULTIFUNKTIONELLEN | ENTHONE INC. (US) | 2009-09-24 | — | — | WO | claimed |
| US-20070032489-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | US | claimed |
| EP-1732896-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | Aventis Pharmaceuticals Inc. (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005097750-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-20 | — | — | WO | claimed |
| EP-0226016-A1 | Process for inhibiting hydrogen-induced corrosion of metallic materials | BAYER AG (DE) | 1987-06-24 | — | — | EP | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |
| JP-6329640-A | — | — | None | — | — | JP | disclosed |
| US-20260138071-A1 | SULFIDE GAS REMOVAL PROCESS | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2026-05-21 | — | — | US | disclosed |
| EP-4681712-A2 | PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS | VIFOR (INTERNATIONAL) AG (CH) | 2026-01-21 | — | — | EP | disclosed |
| EP-0224151-A2 | 2-Substituted-[2-substituted-amino]-N-aralkyl-3-[indol-3-yl]propanamides | WARNER-LAMBERT COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0034116-A2 | N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines | BERLEX LABORATORIES, INC. (US) | 1981-08-19 | — | — | EP | disclosed |
| US-4264494-A | Chromium complex dyestuffs for natural polyamides and synthetic nylons | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202795-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | PARP1, PARP2, PARP3 | POLB 96/4885NPC1 4028/4885RAB9A 3524/4885 |
| US-20070032489-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | PARP1, PARP2, PARP3 | POLB 96/4885NPC1 4028/4885RAB9A 3524/4885 |
| US-20260138071-A1 | SULFIDE GAS REMOVAL PROCESS | SAMM50, SRSF1, GTF2F1 | POLB 2388/4885NPC1 1662/4885RAB9A 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.