SCHEMBL29620366

SCHEMBL29620366

NCCc1nc2ccccc2[nH]1

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.72
NPC1 O15118 1/20 0.66
RAB9A P51151 1/20 0.66
DDAH1 O94760 1/20 0.61
RAD52 P43351 1/20 0.60
UBE2N P61088 1/20 0.60
CHRM1 P11229 1/20 0.60
IDO1 P14902 1/20 0.60
PDE10A Q9Y233 2/20 0.58
KDM4E B2RXH2 1/20 0.58
GAA P10253 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL524002 1.00 POLB (0.72) POLBNPC1RAB9ADDAH1RAD52
Hydrochloric Acid SCHEMBL2454024 0.98 POLB (0.70) POLBNPC1RAB9ADDAH1RAD52
Hydrochloric Acid SCHEMBL28373229 0.98 POLB (0.70) POLBNPC1RAB9ADDAH1RAD52
Hydrochloric Acid SCHEMBL7413158 0.96 POLB (0.68) POLBNPC1RAB9ADDAH1RAD52
SCHEMBL29505763 0.89 POLB (0.79) POLBNPC1RAB9ADDAH1CHRM1
SCHEMBL856769 0.89 POLB (0.79) POLBNPC1RAB9ADDAH1CHRM1
SCHEMBL230157 0.88 POLB (0.84) POLBNPC1RAB9ADDAH1CHRM1
Hydrochloric Acid SCHEMBL8327038 0.87 POLB (0.77) POLBNPC1RAB9ADDAH1CHRM1
SCHEMBL1884524 0.87 POLB (0.83) POLBNPC1RAB9ADDAH1CHRM1
SCHEMBL4704495 0.86 POLB (0.80) POLBNPC1RAB9ADDAH1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101698-A1 HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF PROTAGONIST THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
EP-4681712-A2 PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-01-21 EP disclosed
EP-4126854-B1 PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-12-03 EP disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
CN-119528886-B Shearing inhibitor for pre-miR-21 post-transcriptional processing and preparation method and application thereof 广东工业大学 2025-04-18 CN disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
CN-119528886-A Shearing inhibitor for pre-miR-21 post-transcriptional processing and preparation method and application thereof 广东工业大学 2025-02-28 CN disclosed
CN-119384474-A Liquid composition and optical film 日本瑞翁株式会社 2025-01-28 CN disclosed
CN-119053889-A Multilayer film, method for producing same, polarizing plate, and organic electroluminescent image display device 日本瑞翁株式会社 2024-11-29 CN disclosed
CN-117957114-A Multilayer film, optical multilayer film, and method for producing same 日本瑞翁株式会社 2024-04-30 CN disclosed
US-20240124404-A1 COMPOSITION FOR TREATING DISEASES RELATED TO ADVANCED GLYCATION END PRODUCTS COMPRISING INDOLE DERIVATIVE METACEN THERAPEUTICS (KR) 2024-04-18 US disclosed
US-20240124305-A1 PROCESS FOR SIMULTANEOUS REMOVAL OF HYDROGEN SULFIDE AND HEAVY METALS KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-04-18 US disclosed
EP-4326717-A1 MODIFIED FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2024-02-28 EP disclosed
CN-116829532-A Substituted cyclohexane carboxamides, their preparation and their therapeutic use 赛诺菲 2023-09-29 CN disclosed
CN-116810216-A Water-soluble pre-flux and surface treatment method 株式会社田村制作所 2023-09-29 CN disclosed
CN-111443415-B Polarizing plate 住友化学株式会社 2023-08-01 CN disclosed
CN-111781342-B Sensitization type SPR immunosensor constructed by gold-magnetic composite nano-meter detects carbendazim 中国医学科学院药用植物研究所 2023-07-07 CN disclosed
WO-2022223689-A1 MODIFIED FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2022-10-27 WO disclosed
EP-3841102-B1 TETRAHYDROPYRIDOPYRIMIDINE DERIVATIVES AS AHR MODULATORS JAGUAHR THERAPEUTICS PTE LTD (SG) 2022-09-14 EP disclosed
CN-110229366-B Multilayer film and method for producing same 日本瑞翁株式会社 2022-05-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124404-A1 COMPOSITION FOR TREATING DISEASES RELATED TO ADVANCED GLYCATION END PRODUCTS COMPRISING INDOLE DERIVATIVE AGER, IDO1, IAPP POLB 3978/4885NPC1 3274/4885RAB9A 3408/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS POLB 1532/4885NPC1 2316/4885RAB9A 583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.