SCHEMBL230157

SCHEMBL230157

c1ccc2[nH]c(CCc3nc4ccccc4[nH]3)nc2c1

nearest known ligand 0.84

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.84
NPC1 O15118 1/20 0.81
RAB9A P51151 1/20 0.81
PDE10A Q9Y233 2/20 0.71
DDAH1 O94760 1/20 0.70
CHRM1 P11229 1/20 0.68
GAA P10253 1/20 0.66
BCHE P06276 1/20 0.63
MAPT P10636 1/20 0.63
PKM P14618 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7854448 0.91 POLB (0.92) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL7006523 0.91 POLB (1.00) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL30583066 0.90 RAB9A (1.00) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL784574 0.90 RAB9A (1.00) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL7856311 0.90 POLB (0.96) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL7854826 0.90 POLB (0.96) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL30701864 0.90 POLB (0.96) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL4249670 0.90 POLB (0.75) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL7856315 0.90 POLB (0.96) POLBNPC1RAB9APDE10ADDAH1
SCHEMBL30701863 0.90 POLB (0.96) POLBNPC1RAB9APDE10ADDAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8182718-B2 Ligand exchange thermochromic systems and high ε ligands for same PLEOTINT, L.L.C. (US) 2012-05-22 US claimed
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-05-30 US disclosed
EP-4347544-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES Dow Technology Investments LLC (US) 2024-04-10 EP disclosed
CN-117242047-A Process for the vapor phase hydrogenation of aldehydes 陶氏技术投资有限责任公司 2023-12-15 CN disclosed
CN-116810216-A Water-soluble pre-flux and surface treatment method 株式会社田村制作所 2023-09-29 CN disclosed
EP-3196048-B1 RUBBER COMPOSITION FOR TIRES, PNEUMATIC TIRE, AND AN AIRLESS TIRE SUMITOMO RUBBER IND (JP) 2020-12-16 EP disclosed
US-10507692-B2 Rubber compound for tires, pneumatic tire, and an airless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-12-17 US disclosed
EP-2970074-B1 HYDROFORMYLATION PROVESS USING A HETEREOCYCLIC AGENT AS CATALYTIC STABILIZING AGENT DOW TECHNOLOGY INVESTMENTS LLC (US) 2019-04-24 EP disclosed
US-20170305192-A1 RUBBER COMPOUND FOR TIRES, PNEUMATIC TIRE, AND AN AIRLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-26 US disclosed
EP-2526129-B1 ETHYLENE POLYMERISATION PROCESS SAUDI BASIC IND CORP (SABIC) (SA) 2017-09-27 EP disclosed
US-6255091-B1 ASSAYING FOR ENHANCED INHIBITION OF SERINE PROTEASE IN A MEDIUM THAT IS DEVOID OF DISSACIATED DIVALENT METAL CATIONS AXYS PHARMACEUTICALS, INC. 2001-07-03 US disclosed
EP-0943008-A1 METAL MEDIATED SERINE PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 1999-09-22 EP disclosed
EP-0791671-B1 Surface treating agent for copper or copper alloy SHIKOKU CHEM (JP) 1999-06-16 EP disclosed
EP-0873292-A1 IMPROVED METAL-LIGAND COMPLEX CATALYZED PROCESSES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-10-28 EP disclosed
US-5795409-A MIXTURE OF A (BENZ)IMIDAZOLE COMPOUND, CHELATE COMPOUND AND IRON SHIKOKU CHEMICALS CORPORATION (JP) 1998-08-18 US disclosed
WO-1998022619-A1 METAL MEDIATED SERINE PROTEASE INHIBITORS ARRIS PHARMACEUTICAL CORPORATION (US) 1998-05-28 WO disclosed
US-5731472-A HETEROCYCLIC NITROGEN COMPOUNDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-03-24 US disclosed
EP-0791671-A1 Surface treating agent for copper or copper alloy SHIKOKU CHEMICALS CORPORATION (JP) 1997-08-27 EP disclosed
WO-1997020798-A1 IMPROVED METAL-LIGAND COMPLEX CATALYZED PROCESSES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-06-12 WO disclosed
US-3955920-A ION EXCHANGING HENKEL & CIE G.M.B.H. (DT) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES ADH1C, ADH5, ALDH2 POLB 32/4885NPC1 4654/4885RAB9A 2415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.