⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87711 | 1.00 | — | — | |
| SCHEMBL523957 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31624810 | 0.98 | — | — | |
| SCHEMBL9067713 | 0.83 | — | — | |
| SCHEMBL12564801 | 0.81 | ALDH1A1 (0.50) | — | |
| SCHEMBL2033238 | 0.80 | — | — | |
| SCHEMBL4578719 | 0.79 | — | — | |
| SCHEMBL7356952 | 0.77 | — | — | |
| SCHEMBL1098287 | 0.77 | — | — | |
| SCHEMBL7793918 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172060-A | Razaxaban, synthesis and refining methd | 苏州二叶制药有限公司 | 2019-08-27 | — | — | CN | claimed |
| CN-106008491-B | A kind of preparation method of razaxaban | 苏州汇和药业有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-106008491-A | Preparation method of Rivaroxaban | 苏州汇和药业有限公司 | 2016-10-12 | — | — | CN | claimed |
| US-11040048-B2 | Medicament for treating influenza characterized by combining a Cap-dependent endonuclease inhibitor and an anti-influenza drug | SHIONOGI & CO., LTD. (JP) | 2021-06-22 | — | — | US | disclosed |
| US-20200261481-A1 | A MEDICAMENT FOR TREATING INFLUENZA CHARACTERIZED BY COMBINING A CAP-DEPENDENT ENDONUCLEASE INHIBITOR AND AN ANTI-INFLUENZA DRUG | SHIONOGI & CO., LTD. (JP) | 2020-08-20 | — | — | US | disclosed |
| CN-106008491-B | A kind of preparation method of razaxaban | 苏州汇和药业有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-106008491-B | A kind of preparation method of razaxaban | 苏州汇和药业有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-106008491-A | Preparation method of Rivaroxaban | 苏州汇和药业有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106008491-A | Preparation method of Rivaroxaban | 苏州汇和药业有限公司 | 2016-10-12 | — | — | CN | disclosed |
| US-9187478-B2 | Substituted naphthyridines and their use as medicaments | Boehringer Ingellheim International GmbH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-9187478-B2 | Substituted naphthyridines and their use as medicaments | Boehringer Ingellheim International GmbH (DE) | 2015-11-17 | — | — | US | disclosed |
| WO-2005070891-A2 | COMPOUNDS AND METHODS OF USE | AMGEN INC (US) | 2005-08-04 | — | — | WO | disclosed |
| US-20050143376-A1 | Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones | GORDEEV MIKHAIL F (US) | 2005-06-30 | — | — | US | disclosed |
| US-6884813-B2 | Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 2005-04-26 | — | — | US | disclosed |
| US-6743811-B2 | MICROBIOCIDES | PHARMACIA & UPJOHN COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-20030232812-A1 | Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones | PHARMACIA & UPJOHN COMPANY | 2003-12-18 | — | — | US | disclosed |
| US-20020169191-A1 | Oxazolidinone compounds and methods of preparation and use thereof | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-14 | — | — | US | disclosed |
| US-6441005-B1 | BACTERICIDES, ANTIBIOTICS AND MICROBIOCIDES | PHARMACIA & UPJOHN COMPANY | 2002-08-27 | — | — | US | disclosed |
| EP-1200416-A1 | OXAZOLIDINONES AND THEIR USE AS ANTIINFECTIVES | Pharmacia & Upjohn Company (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009107-A1 | OXAZOLIDINONES AND THEIR USE AS ANTIINFECTIVES | PHARMACIA & UPJOHN COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |