Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236899 | 1.00 | ALDH1A1 (0.41) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL5236906 | 1.00 | ALDH1A1 (0.41) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL5235218 | 0.81 | ALDH1A1 (0.48) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL27516286 | 0.81 | ALDH1A1 (0.48) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL5235668 | 0.81 | ALDH1A1 (0.48) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL2525596 | 0.80 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL18186635 | 0.75 | TSHR (0.47) | RAB9ASMN1; SMN2KMT2AMMP2MMP3 | |
| SCHEMBL16756891 | 0.74 | CA1 (0.40) | KMT2AFOLH1MMP2MMP3 | |
| SCHEMBL16757114 | 0.72 | TDP1 (0.39) | MEN1KMT2A | |
| SCHEMBL25486668 | 0.71 | TSHR (0.42) | RAB9ASMN1; SMN2KMT2AMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | disclosed |