Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236899 | 0.80 | ALDH1A1 (0.41) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL5236906 | 0.80 | ALDH1A1 (0.41) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL2523003 | 0.80 | ALDH1A1 (0.58) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL2527646 | 0.79 | ALDH1A1 (0.56) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL2524844 | 0.79 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL15876445 | 0.79 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL2522823 | 0.73 | ALDH1A1 (0.56) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL8352039 | 0.73 | ALDH1A1 (0.52) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL18222999 | 0.72 | ALDH1A1 (0.67) | ALDH1A1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL9939048 | 0.70 | LMNA (0.53) | ALDH1A1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507472-B2 | Bicyclic pyridinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | disclosed |
| US-20110251178-A1 | Bicyclic Pyridinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251178-A1 | Bicyclic Pyridinylpyrazoles | PLPBP, PNPO, PIR | ALDH1A1 1179/4885RAB9A 3773/4885SMN1; SMN2 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.